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ultrasensitive proteomics
Ultrasensitive single-cell proteomics methods:
1) Chemical labeling — enhance signal
2) Containerless sample preparation — minimize loss
3) Novel algorithms — improve detection
Big data analysis platform
Better data analysis platforms for omics data:
1) Data visualization
2) Multi-omics data integration
3) Machine learning methods
Cancer Early diagnostics
1) Exosome proteome — patient classification
2) Circulating tumor cells — liquid biopsy
3) Extracellular matrix — cancer metastasis
Classify patients' response with 100 μl of blood
DISEASE MODELS
1) Cancer — tumor cell heterogeneity, ovarian, breast
2) Neurodegenerative diseases — neuron profiling, pain
3) Asthma — HLA complex
4) Cardiovascular disease — fetal hypoxia
5) Infectious diseases — S. mansoni, host defense
